GS100 & GS200 Benchtop Sequencers

Greater flexibility and simplicity in benchtop sequencing

The GS Series brings together flexible throughput, streamlined operation, and innovative LumoSeq chemistry, giving laboratories more freedom to plan sequencing runs, manage different sample volumes, and support a broad range of research and clinical laboratory applications.

Flexible Throughput for Diverse Use

With a broad output range from 25M to 400M reads, the GS Series enables flexible run configuration for different sample volumes and project needs.

Mixed-Library Sequencing in a Single Run

Sequence multiple application libraries together in one run, with real-time configuration to generate the read lengths required for different workflows.

High-Accuracy Sequencing Powered by Core Technologies

Built on the GS sequencing system, it integrates CYGNUS-developed LumoSeq technology to deliver high-quality, high-accuracy sequencing across diverse library types, without the need for additional balancing.

An Integrated Workflow from Sequencing to Insight

Paired with the CYGNUS X1 Bioinformatics System, the GS Series provides a streamlined end-to-end solution, covering the full workflow from sequencing to data analysis.

Explore our Technology

Simplify Sequencing. Focus on Discovery.

From instrument setup to sequencing runs, the GS Series offers an intuitive user experience and consistent sequencing performance, helping laboratories work with greater efficiency.

2.5Gb ~ 120Gb

Output

25M ~ 400M

Reads per run

6.5h ~ 35h

Turn-around time

Q40 ≥ 85%

High data quality

Simplify Sequencing. Focus on Discovery.

Advancing Sequencing. Expanding Possibilities.

Discover the latest GS Series innovations, product updates, and research highlights, bringing new possibilities to sequencing and scientific discovery.

GS in Research October 12 2026

Frontiers in Microbiology | Cygnus GS100 Enables Whole-Genome Characterization of Listeria monocytogenes in Neonatal Sepsis

Product Update October 13 2026

Go Further with PE300 | Longer Reads for Broader Sequencing Applications

Find sequencing applications and focus areas for your research.

Applications

DNA Sequencing

RNA Sequencing

Epigenomics

Focus Areas

Reproductive Health

Pathogen Detection

Genetic Disease

Simple Setup. Efficient Sequencing.

20-minute setup, 6.5–35-hour sequencing, and automated data transfer to the bioinformatics workstation.

Performance Parameters

Flexible sequencing for a range of research needs. Explore output, run time, and data quality across supported configurations, with consistent Q30 and Q40 specifications across read lengths.

Data Output (Gb)

Read Length	25Mᵃ	50Mᵃ	100Mᵃ	200Mᵇ	400Mᵇ
1 × 50 bp	—	—	5	10	20
1 × 100 bp	2.5	5	10	20	40
2 × 100 bp	—	—	20	40	80
2 × 150 bp	7.5	15	30	60	120
2 × 300 bp	—	30	—	—	—

ᵃ The 25M, 50M, and 100M read tiers are available for both GS100 and GS200.

ᵇ The 200M and 400M read tiers are available for GS200 only.

— Not listed in the original table.

Run Time (hours)

Read Length	25Mᵃ	50Mᵃ	100Mᵃ	200Mᵇ	400Mᵇ
1 × 50 bp	—	—	6.5	6.6	7.5
1 × 100 bp	8	9.5	8.5	9.5	11.5
2 × 100 bp	—	—	16.5	18.5	22
2 × 150 bp	19.5	26	24	28	35
2 × 300 bp	—	72	—	—	—

ᵃ The 25M, 50M, and 100M read tiers are available for both GS100 and GS200.

ᵇ The 200M and 400M read tiers are available for GS200 only.

— Not listed in the original table.

Sequencing Quality*

Quality Metric	Specification
Q30	≥ 95%
Q40	≥ 85%

*Q30 and Q40 specifications are consistent across all GS100 and GS200 configurations.

Instrument Specifications

Dimensions (W x D x H)	55cm x 65cm x 65cm
Package Dimensions (W x D x H)	67.6cm x 90cm x 98cm
Weight	90kg
Crated weight	165kg

Application Parameters

Estimated sample throughput for key applications

Application type	25M	50M	100M	200M	400M
mNGS SE50 20M Reads	1	2	5	10	20
tNGS SE100 1M Reads	24	48	96	192	384
Targeted panel of tumor (tissue) PE150 1Gb/sample	7	14	30	60	120
Targeted panel of tumor (blood) PE150 6Gb/sample	-	2	5	10	20
PGT-A SE100 3M/Reads	8	16	32	64	128
NIPT SE50 6M/Reads	4	8	16	32	64
WES PE150 15Gb/sample	-	1	1-2	3-5	6-10

Resources

GS Series Brochure

Specifications, configurations and ordering information in one document.

Download

GS Series Publications

Research publications featuring GS Series sequencing systems across diverse applications.

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Technical Support

Expert support from application scientists, engineers and bioinformaticians across instrument operation, applications and data analysis.

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